Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4.

作者: J-Y Kato , H Matsushime , SW Hiebert , ME Ewen , CJ Sherr

DOI: 10.1101/GAD.7.3.331

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摘要: … D-type cyclins activated cdk4 enzyme activity, whereas cyclins A, B1, and E did not. When Sf9 cells were coinfected with baculovirus vectors encoding human pRb and murine D-… and D-…

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