The transcriptional program in the response of human fibroblasts to serum.
作者： Vishwanath R Iyer , Michael B Eisen , Douglas T Ross , Greg Schuler , Troy Moore
DOI: 10.1126/SCIENCE.283.5398.83
关键词:
摘要: The temporal program of gene expression during a model physiological response human cells, the fibroblasts to serum, was explored with complementary DNA microarray representing about 8600 different genes. Genes could be clustered into groups on basis their patterns in this program. Many features transcriptional appeared related physiology wound repair, suggesting that play larger and richer role complex multicellular than had previously been appreciated.
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Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nature Genetics. ,vol. 14, pp. 457- 460 ,(1996) , 10.1038/NG1296-457
Jeffrey A. Winkles, Serum- and Polypeptide Growth Factor-Inducible Gene Expression in Mouse Fibroblasts Progress in Nucleic Acid Research and Molecular Biology. ,vol. 58, pp. 41- 78 ,(1997) , 10.1016/S0079-6603(08)60033-1
Wilhelm Krek, James A. DeCaprio, [7] Cell synchronization Methods in Enzymology. ,vol. 254, pp. 114- 124 ,(1995) , 10.1016/0076-6879(95)54009-1
Tony Hunter, Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling Cell. ,vol. 80, pp. 225- 236 ,(1995) , 10.1016/0092-8674(95)90405-0
Mark S. Boguski, Gregory D. Schuler, ESTablishing a human transcript map. Nature Genetics. ,vol. 10, pp. 369- 371 ,(1995) , 10.1038/NG0895-369
M. Schena, D. Shalon, R. W. Davis, P. O. Brown, Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray Science. ,vol. 270, pp. 467- 470 ,(1995) , 10.1126/SCIENCE.270.5235.467
Andy C.-M. Chang, Jackie Janosi, Miriam Hulsbeek, Debora de Jong, Katherine J. Jeffrey, Jane R. Noble, Roger R. Reddel, A novel human cDNA highly homologous to the fish hormone stanniocalcin Molecular and Cellular Endocrinology. ,vol. 112, pp. 241- 247 ,(1995) , 10.1016/0303-7207(95)03601-3
Gregory D. Schuler, Pieces of the puzzle: expressed sequence tags and the catalog of human genes. Journal of Molecular Medicine. ,vol. 75, pp. 694- 698 ,(1997) , 10.1007/S001090050155
K J Livak, S J Flood, J Marmaro, W Giusti, K Deetz, Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. Genome Research. ,vol. 4, pp. 357- 362 ,(1995) , 10.1101/GR.4.6.357
Juhani Leppäluoto, Heikki Ruskoaho, Endothelin peptides: biological activities, cellular signalling and clinical significance. Annals of Medicine. ,vol. 24, pp. 153- 161 ,(1992) , 10.3109/07853899209147813