Methionine positron emission tomography of recurrent metastatic brain tumor and radiation necrosis after stereotactic radiosurgery: is a differential diagnosis possible?
作者： Naohiro Tsuyuguchi , Ichiro Sunada , Yoshiyasu Iwai , Kazuhiro Yamanaka , Kiyoaki Tanaka
DOI: 10.3171/JNS.2003.98.5.1056
关键词:
摘要: Object. In this study the authors examined how to differentiate radiation necrosis from recurrent metastatic brain tumor following stereotactic radiosurgery by using positron emission tomography (PET) with l-[methyl-11C]methionine (MET). Methods. 21 adult patients suspected or injury, MET-PET scans were obtained. These had previously undergone and subsequent contrast-enhanced magnetic resonance (MR) examinations before nuclear medicine imaging. Positron images obtained as a static scan of 10 minutes performed 20 after injection 370 MBq MET. On scans, portion highest accumulation MET was selected region interest (ROI), ratio tissue normal (T/N) defined mean counts radioisotope per pixel in divided gray matter. The standardized uptake value (SUV) was...
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