HÆMOSTATIC FUNCTION AND PLATELET POLYUNSATURATED FATTY ACIDS IN ESKIMOS
作者： J Dyerberg , H.O Bang
DOI: 10.1016/S0140-6736(79)91490-9
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摘要: Abstract Death from cardiovascular disease is rare among Eskimos. Haemostasis was investigated in twenty-one Greenland Eskimos and age sex matched Danish controls. Platelet lipid analysis demonstrated that a high consumption of ω-3 polyunsaturated fatty acids (such as cis 5, 8, 11, 14, 17-eicosapentaenoic acid [C20:5]) by increased the proportion platelets. The had significantly longer bleeding-time due to reduction platelet aggregation. It suggested C20:5 platelets converted vascular-wall tissue an anti-aggregatory prostacyclin. Partial dietary substitution arachidonic eicosapentaenoic may reduce incidence thrombotic disorders, including myocardial infarction.
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