Clinical Feasibility of Continuously Monitored Data for Heart Rate, Physical Activity, and Sleeping by Wearable Activity Trackers in Patients with Thyrotoxicosis: Protocol for a Prospective Longitudinal Observational Study

摘要: Background: Thyrotoxicosis is a common disease caused by an excess of thyroid hormones. The prevalence thyrotoxicosis about 2% and 70-90% cases are Graves' disease, autoimmune which has high recurrence rate when treated with antithyroid drugs such as methimazole or propylthiouracil. clinical symptoms signs include palpitation, weight loss, restlessness, difficulty sleeping. Although these changes in can be detected currently available wearable activity trackers, there have been few trials the application devices patients thyrotoxicosis. Objective: aim this study to investigate applicability device-generated data management We analyzing continuously monitored for heart rate, physical activity, sleep during their course after treatment. Methods: Thirty thyrotoxic 10 control subjects were enrolled at Seoul National University Bundang Hospital. Heart being using Fitbit Charge HR 2. Clinical including anthropometric measures, function test, hyperthyroidism symptom scale recorded. Results: Study enrollment began December 2016, intervention follow-up phases ongoing. results analysis expected September 2017. Conclusions: This will provide foundational feasibility trial applications biosignal measurements differential diagnosis, prediction course, early detection recurrence, treatment Trial: ClinicalTrials.gov NCT03009357; https://clinicaltrials.gov/ct2/show/NCT03009357 (Archived WebCite http://www.webcitation.org/6wh4MWPm2) [JMIR Res Protoc 2018;7(2):e49]