Do recurring outbreaks of a type of infectious immune impairment trigger cyclic changes in the gender ratio at birth

摘要: Unexpected step-like increases in emergency medical hospital admissions, general practitioner (GP) referrals, and wider health care costs that appear to repeat at an interval between three eight years length have been observed the United Kingdom (UK) other countries. Based on observation step changes be restricted a group of diagnoses associated with infection or inflammation, it has proposed outbreaks unknown type infectious immune impairment are responsible for cycle. Both inflammation implicated gender ratio (male-to-female births) humans animals, this development presents opportunity test outbreak hypothesis. Monthly live births England Wales 1980 2008 were studied. After adjusting effects solar sunspot cycle season ratio, pattern residual (actual minus predicted) appears align admissions costs. It each initiates cascade condition-specific effects, which include conception and/or fetal loss along adults, more specifically elderly. An additional peak conceptions September, October, November 1986 correspond impact fallout from Chernobyl nuclear accident April seems confirm results studies low levels radiation ratio. Biomed . Int 2013; 4: 26-39. ©2013 Biomedicine International,