FGFR1 is amplified during the progression of in situ to invasive breast carcinoma.
作者： Min Hye Jang , Eun Joo Kim , Yoomi Choi , Hee Eun Lee , Yu Jung Kim
DOI: 10.1186/BCR3239
关键词:
摘要: Introduction Gene amplification is an important mechanism for activating oncogenes in malignant tumors. Although of HER2, C-MYC, CCND1 and FGFR1 has been reported breast cancers, their role the progression situ to invasive carcinoma unclear. To investigate this question we compared frequencies these genes pure ductal (DCIS), DCIS associated with carcinoma, carcinoma.
biomedcentral.com
springer.com
core.ac.uk
breast-cancer-research.com参考文章(48)
Robert Zeillinger, Geneviève Louason, Frank Courjal, Paul Speiser, Charles Theillet, Carmen Rodriguez, Joelle Simony-Lafontaine, Marguerite Cuny, Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups. Cancer Research. ,vol. 57, pp. 4360- 4367 ,(1997)
Frank Courjal, Charles Theillet, Comparative Genomic Hybridization Analysis of Breast Tumors with Predetermined Profiles of DNA Amplification Cancer Research. ,vol. 57, pp. 4368- 4377 ,(1997)
Anne Letessier, Fabrice Sircoulomb, Christophe Ginestier, Nathalie Cervera, Florence Monville, Véronique Gelsi-Boyer, Benjamin Esterni, Jeannine Geneix, Pascal Finetti, Christophe Zemmour, Patrice Viens, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Daniel Birnbaum, Max Chaffanet, Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers BMC Cancer. ,vol. 6, pp. 245- 245 ,(2006) , 10.1186/1471-2407-6-245
J. Adelaide, P. Finetti, I. Bekhouche, L. Repellini, J. Geneix, F. Sircoulomb, E. Charafe-Jauffret, N. Cervera, J. Desplans, D. Parzy, E. Schoenmakers, P. Viens, J. Jacquemier, D. Birnbaum, F. Bertucci, M. Chaffanet, Integrated profiling of basal and luminal breast cancers. Cancer Research. ,vol. 67, pp. 11565- 11575 ,(2007) , 10.1158/0008-5472.CAN-07-2536
Els C Robanus-Maandag, Cathy AJ Bosch, Petra M Kristel, Augustinus AM Hart, Ian F Faneyte, Petra M Nederlof, Johannes L Peterse, Marc J van de Vijver, Association of C‐MYC amplification with progression from the in situ to the invasive stage in C‐MYC‐amplified breast carcinomas The Journal of Pathology. ,vol. 201, pp. 75- 82 ,(2003) , 10.1002/PATH.1385
Wa Xian, Kathryn L. Schwertfeger, Tracy Vargo-Gogola, Jeffrey M. Rosen, Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. Journal of Cell Biology. ,vol. 171, pp. 663- 673 ,(2005) , 10.1083/JCB.200505098
Bircan Erbas, Elena Provenzano, Jane Armes, Dorota Gertig, The natural history of ductal carcinoma in situ of the breast: a review Breast Cancer Research and Treatment. ,vol. 97, pp. 135- 144 ,(2006) , 10.1007/S10549-005-9101-Z
S L Deming, S J Nass, R B Dickson, B J Trock, C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance British Journal of Cancer. ,vol. 83, pp. 1688- 1695 ,(2000) , 10.1054/BJOC.2000.1522
S M. Rodriguez-Pinilla, R. L Jones, M. B K Lambros, E. Arriola, K. Savage, M. James, S. E Pinder, J. S Reis-Filho, MYC amplification in breast cancer: a chromogenic in situ hybridisation study Journal of Clinical Pathology. ,vol. 60, pp. 1017- 1023 ,(2006) , 10.1136/JCP.2006.043869
Sabine Glöckner, Ulrich Lehmann, Nadine Wilke, Wolfram Kleeberger, Florian Länger, Hans Kreipe, Amplification of growth regulatory genes in intraductal breast cancer is associated with higher nuclear grade but not with the progression to invasiveness. Laboratory Investigation. ,vol. 81, pp. 565- 571 ,(2001) , 10.1038/LABINVEST.3780265