Hematological and biochemical investigations on the effect of vitamin E and C on Oreochromis niloticus exposed to zinc oxide nanoparticles
作者： Ali Alkaladi , Nasr A.M. Nasr El-Deen , Mohamed Afifi , Osama A. Abu Zinadah
DOI: 10.1016/J.SJBS.2015.02.012
关键词:
摘要: This study was carried out to determine the LC50 of zinc oxide nanoparticles (ZnONPs) on Oreochromis niloticus and investigate effect vitamin E C hematological biochemical alterations induced by two sublethal concentrations (1 2 mg/L) ZnONPs. One hundred eighty fish were used for studying lethal For twenty-five males O. equally divided into five groups, control, second third treated with 1 2 mg/L ZnONPs respectively. The fourth fifth exposed same plus vitamins C. results revealed that 96 h 3.1 ± 0.4 mg/L. presence normocytic normochromic anemia in groups (2, 3 5) along experiment period. 4th group showed at 7th day microcytic hypochromic 15th day. Leukocytosis, heterophilia, lymphopenia monocytopenia recorded all compared normal control. At heteropenia, reported groups. A significant increase serum levels alkaline phosphatase, aminotransferases, urea, creatinine erythrocytic nuclear morphological abnormalities experimental periods Serum total protein albumin significantly decreased period Addition diet (groups 4 improved measured parameters (2 3) which only.
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