Methodologies to decipher the cell secretome.
作者： Paromita Mukherjee , Sridhar Mani
DOI: 10.1016/J.BBAPAP.2013.01.022
关键词:
摘要: Abstract The cell secretome is a collection of proteins consisting transmembrane (TM) and secreted by cells into the extracellular space. A significant portion (~ 13–20%) human proteome consists secretory proteins. play important roles in migration, signaling communication. There plethora methodologies available like Serial Analysis Gene Expression (SAGE), DNA microarrays, antibody arrays bead-based arrays, mass spectrometry, RNA sequencing yeast, bacterial mammalian secretion traps to identify secretomes. are many advantages disadvantages using any above methods. This review aims discuss along with their potential part Special issue on Secretome. article Issue entitled: An Updated
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