FOLFOX and FLOX regimens for the adjuvant treatment of resected stage II and III colon cancer.

作者: Saima Sharif , Michael J O'Connell , Greg Yothers , Samia Lopa , Norman Wolmark

DOI: 10.1080/07357900802132550

关键词:

摘要: The MOSAIC trial showed that the use of adjuvant oxaliplatin and an infusional regimen 5-FU/LV in treatment stage II/III colon cancer improved disease-free survival (DFS). NSABP's C-07 evaluated addition to a weekly Roswell Park bolus found similar improvement DFS. benefit appears be independent used. This paper reviews efficacy toxicities these two regimens is meant serve as guide for clinical practice.

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