Structure of cortical microcircuit theory.

摘要: Recent experimental and theoretical investigations have made considerable advances in three major areas relating to the structural basis of quantitative cortical microcircuit theory. The first concerns nature cellular units, encompassing increasingly precise identification progressively more complete listing individual species that constitute various networks. second element addresses problem heterogeneity, including demonstration importance cell variability within defined interneuronal populations application Shannon-Wiener diversity index for assessment number relative abundance species. third component relates discovery basic topological principles underlying circuit wiring, revealing a surprising order architectural design These new deepen our understanding computational embedded microcircuits, they also provide novel opportunities building realistic models mammalian microcircuits.