A genetically tractable model of human glioma formation.

作者: Roger E. McLendon , Christopher M. Counter , Darell D. Bigner , Jeremy N. Rich , Chuanhai Guo

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摘要: Gliomas remain one of the deadliest forms of cancer. Improved therapeutics will require a better understanding of the molecular nature of these tumors. We, therefore, mimicked the …

参考文章(28)
S. C. Schold, D. D. Bigner, T. R. Jones, L. F. Eng, S. H. Bigner, Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression. American Journal of Pathology. ,vol. 105, pp. 316- 327 ,(1981)
Tanya S. Surawicz, Faith Davis, Sally Freels, Edward R. Laws Jr., Herman R. Menck, Brain tumor survival: results from the National Cancer Data Base. Journal of Neuro-oncology. ,vol. 40, pp. 151- 160 ,(1998) , 10.1023/A:1006091608586
B Westermark, M Nister, Mechanisms of altered growth control. Growth factors Edward Arnold Publishers Ltd. pp. 83- ,(1998)
Karlyne M. Reilly, Dagan A. Loisel, Roderick T. Bronson, Margaret E. McLaughlin, Tyler Jacks, Nf1 ; Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects Nature Genetics. ,vol. 26, pp. 109- 113 ,(2000) , 10.1038/79075
William C. Hahn, Christopher M. Counter, Ante S. Lundberg, Roderick L. Beijersbergen, Mary W. Brooks, Robert A. Weinberg, Creation of human tumour cells with defined genetic elements Nature. ,vol. 400, pp. 464- 468 ,(1999) , 10.1038/22780
M Stevenson, D J Volsky, Activated v-myc and v-ras oncogenes do not transform normal human lymphocytes. Molecular and Cellular Biology. ,vol. 6, pp. 3410- 3417 ,(1986) , 10.1128/MCB.6.10.3410
N. C. Denko, A. J. Giaccia, J. R. Stringer, P. J. Stambrook, The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 5124- 5128 ,(1994) , 10.1073/PNAS.91.11.5124
Huatao Huang, Rui Reis, Yasuhiro Yonekawa, Jose Manuel Lopes, Paul Kleihues, Hiroko Ohgaki, Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain Pathology. ,vol. 9, pp. 33- 42 ,(2006) , 10.1111/J.1750-3639.1999.TB00207.X
Eric C. Holland, Joseph Celestino, Chengkai Dai, Laura Schaefer, Raymond E. Sawaya, Gregory N. Fuller, Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice Nature Genetics. ,vol. 25, pp. 55- 57 ,(2000) , 10.1038/75596
T Sano, A Asai, K Mishima, T Fujimaki, T Kirino, Telomerase activity in 144 brain tumours. British Journal of Cancer. ,vol. 77, pp. 1633- 1637 ,(1998) , 10.1038/BJC.1998.267