Rotational mechanics of the left ventricle in AL amyloidosis.

摘要: Aims: The aim of this study was to investigate whether alterations in left ventricular (LV) twisting and untwisting motion could be induced by cardiac involvement patients with immunoglobulin light-chain (AL) systemic amyloidosis. Methods Results: Forty-five AL amyloidosis 26 control subjects were evaluated. After standard echocardiographic measurement two-dimensional (2D) speckle tracking echocardiography, LV rotation at both basal apical planes, twisting, rate, longitudinal strain measured. Tissue Doppler imaging (TDI) derived early diastolic peak velocity septal mitral annulus (E′) also Twenty-six 45 classified as having (CA) if the mean value wall thickness ≥ 12 mm or not (NCA) reached. In NCA patients, twist rate increased while they decreased CA making them similar group. Longitudinal reduced only patients. Impaired relaxation indicated E′ values progressively course disease. Conclusions: Both motions are no evidence evident involvement. This finding suggests that impaired induces a compensatory mechanism phase disease, which fails more advanced stage when rates reduced. increase rotational mechanics marker subclinical (Echocardiography 2010;27:1061-1068)