Tuberculosis in Europe: a problem of drug resistance or much more?

摘要: Tuberculosis has re-emerged as a public health concern in high-income countries the last few decades. The European region accounts for only 5% of world TB cases. incidence new cases Europe varies from very low rates Scandinavian (six to eight cases/100,000 population) high 231 population Tajikistan; Russian Federation is eleventh among 22 high-burden countries. estimated detection rate sputum smear-positive pulmonary and treatment success 2007 were poor compared with other WHO regions: 51% diagnosed 70% them completed full course anti-TB therapy, which still long way World Health Assembly targets (detection infectious successful 85% them). largely attributable increasing number drug-resistant cases: Eastern are those highest multidrug-resistant (MDR)-TB (TB resistant rifampicin isoniazid) world. By end September 2009, at least one case extensively (named XDR-TB defined MDR-TB strain additional resistance any fluoroquinolone, three injectable drugs used treatment) had been reported by 25 Region. In Western Europe, continues cause disease elderly native-born individuals, although high-risk groups including immigrants, prisoners, HIV-infected persons drug addicts significantly contribute overall burden. Improved control requires large coordinated effort all stakeholders, governments, governmental non-governmental institutions, well academic private sectors affected communities.