作者: Matthew D Keller , Elizabeth M Kanter , Chad A Lieber , Shovan K Majumder , Joanne Hutchings
DOI: 10.1155/2008/230307
关键词:
摘要: Epithelial cancers, including those of the skin and cervix, are most common type cancers in humans. Many recent studies have attempted to use Raman spectroscopy diagnose these cancers. In this paper, spectral markers related temporal spatial effects cervical examined through four separate but studies. Results from a clinical cervix study show that previous disease has significant effect on signatures which allow for near 100% classification discriminating versus true normal. A microspectroscopy showed can detect changes due adjacent regions dysplasia or HPV cannot be detected histologically, while spectra may detecting malignancy associated tissues surrounding nonmelanoma Finally, results an organotypic raft culture provided support both vitro results. These add growing body evidence optical spectroscopy, case markers, used subtle tissue cancerous sites go otherwise undetected by conventional histology.