Preoperative platelet to lymphocyte ratio predicts outcome of patients with pancreatic ductal adenocarcinoma after pancreatic resection

摘要: Background Inflammation plays a crucial role in tumor growth, metastasis, and survival. The preoperative platelet-to-lymphocyte ratio (PLR) has been reported as significant prognostic indicators several digestive malignancies. Our objective was to evaluate whether PLR is index resected pancreatic ductal adenocarcinoma. Methods Data from 131 patients who underwent resection for adenocarcinoma were available prospectively maintained database. divided into groups according of Results In univariate multivariate analyses, ≥150 independent risk factor cancer recurrence poor survival, respectively (disease-free survival [DFS]; P= .0014, P = .047; OS, ≤ .01each). Similarly, lymph node moderate or differentiation factors recurrence, whereas diameter, positive surgical margin, patient (P ≤ .05 each). Conclusion with an predictor DFS overall after elective resection. Measurement the may help decision making postoperative management