The PP2A-Associated Protein α4 Is an Essential Inhibitor of Apoptosis
作者： Mei Kong , Casey J Fox , James Mu , Laura Solt , Anne Xu
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摘要: Despite evidence that protein kinases are regulators of apoptosis, a specific role for phosphatases in regulating cell survival has not been established. Here we show that α4, a …
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Seiji Inui, Hideki Sanjo, Kazuhiko Maeda, Hideyuki Yamamoto, Eishichi Miyamoto, Nobuo Sakaguchi, Ig Receptor Binding Protein 1 (α4) Is Associated With a Rapamycin-Sensitive Signal Transduction in Lymphocytes Through Direct Binding to the Catalytic Subunit of Protein Phosphatase 2A Blood. ,vol. 92, pp. 539- 546 ,(1998) , 10.1182/BLOOD.V92.2.539
N Sakaguchi, J Mizutani, H Nakayasu, K Kuwahara, S Inui, K Maeda, T Kawai, Molecular cloning of a cDNA clone encoding a phosphoprotein component related to the Ig receptor-mediated signal transduction Journal of Immunology. ,vol. 154, pp. 2714- 2723 ,(1995)
Alan Storey, Miranda Thomas, Ann Kalita, Catherine Harwood, Daniela Gardiol, Fiamma Mantovani, Judith Breuer, Irene M. Leigh, Greg Matlashewski, Lawrence Banks, Role of a p53 polymorphism in the development of human papillomavirus-associated cancer. Nature. ,vol. 393, pp. 229- 234 ,(1998) , 10.1038/30400
Kornelia Polyak, Yong Xia, Jay L. Zweier, Kenneth W. Kinzler, Bert Vogelstein, A model for p53-induced apoptosis Nature. ,vol. 389, pp. 300- 305 ,(1997) , 10.1038/38525
K. Murata, J. Wu, D. L. Brautigan, B cell receptor-associated protein α4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 10624- 10629 ,(1997) , 10.1073/PNAS.94.20.10624
Martin C. Raff, Social controls on cell survival and cell death Nature. ,vol. 356, pp. 397- 400 ,(1992) , 10.1038/356397A0
Ding Rong Hua, Seiji Inui, Takeshi Yamashita, Kazuhiko Maeda, Katsumasa Takagi, Junji Takeda, Nobuo Sakaguchi, T cell-specific gene targeting reveals that α4 is required for early T cell development European Journal of Immunology. ,vol. 33, pp. 1899- 1906 ,(2003) , 10.1002/EJI.200323720
Katsunori Nakano, Karen H Vousden, PUMA, a novel proapoptotic gene, is induced by p53. Molecular Cell. ,vol. 7, pp. 683- 694 ,(2001) , 10.1016/S1097-2765(01)00214-3
Katrin Düvel, Arti Santhanam, Stephen Garrett, Lisa Schneper, James R Broach, Multiple Roles of Tap42 in Mediating Rapamycin-Induced Transcriptional Changes in Yeast Molecular Cell. ,vol. 11, pp. 1467- 1478 ,(2003) , 10.1016/S1097-2765(03)00228-4
Jie Chen, Randall T. Peterson, Stuart L. Schreiber, α4 Associates with Protein Phosphatases 2A, 4, and 6 Biochemical and Biophysical Research Communications. ,vol. 247, pp. 827- 832 ,(1998) , 10.1006/BBRC.1998.8792