Concordance of interrater assessments of surgical methods to achieve source control of intra-abdominal infections

摘要: Abstract Background Source control, any procedure used to control the source of a major infection, is critical resolution intra-abdominal infections. We sought characterize whether surgeons agree on methods for patients who had persistent infection despite initial surgical treatment and antimicrobials. Methods analyzed decisions in trial comparing tigecycline with imipenem infections were clinical failures abdominal after antibiotics undergoing control. Results found that agreement was least among Acute Physiology Chronic Health Evaluation (APACHE) II scores greater than 15 (κ = −.17, P .533) those complicated appendicitis .08, .446). There excellent perforation .76, 0.002) diverticulitis 1.00, .005). Conclusions Agreement lacking more severely ill appendicitis. These data should be seek optimal management these conditions minimize variability future trials infection.