Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
作者： Shih-Min A Huang , Yuji M Mishina , Shanming Liu , Atwood Cheung , Frank Stegmeier
DOI: 10.1038/NATURE08356
关键词:
摘要: The stability of the Wnt pathway transcription factor β-catenin is tightly regulated by the multi-subunit destruction complex. Deregulated Wnt pathway activity has been implicated in many …
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