Traditional and novel risk factors in older adults: cardiovascular risk assessment late in life.

摘要: As a population-based, longitudinal study of nearly 6000 older American adults, the Cardiovascular Health Study provides an excellent opportunity to assess roles traditional and novel cardiovascular risk factors in development coronary heart disease. investigators have analyzed both factors, such as diabetes, hypertension, smoking, new hemostatic inflammatory markers, exposure infectious agents, genetic determinants. These analyses led several important conclusions. First, adults without previous events tremendous burden subclinical vascular disease, which may change how physicians view factor modification this age group. Second, some lose importance predictors disease among adults. Third, even modest elevations fasting blood glucose or systolic pressure-below levels used define diabetes hypertension-may prognostic implications. Fourth, add further information about Promising potential candidates identified include markers activation, fibrinogen, VIII coagulant activity, C-reactive protein, herpes simplex virus-1 possibly chlamydia. Future investigations will help clarify combination newer best estimate for