作者: Connull Leslie , M. Priyanthi Kumarasinghe , Ian Brown
DOI: 10.1007/978-3-319-79117-3_12
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摘要: While the molecular biology underlying colorectal carcinoma (CRC) has been extensively investigated and distinct pathways described, a comprehensive classification system allowing diagnostic therapeutic subgroups continues to evolve. Tumours with hypermutated phenotype are population consistently identified by all systems, specific predictive attributes. features may be associated tumour site morphology, there is sufficient overlap that testing should reflect consensus recommendations as applied carcinomas rather than those particular pathological features.