Neurochemical Changes in White Matter of Patients with Alzheimer’s Disease

摘要: Most of the elderly persons with dementia belong to a group changes in brain which are considered characteristic for Alzheimer’s disease. It was 1907 that Alzheimer described autopsy findings woman who died at 55 progressive and whom abnormal nerve cells contained tangles fibers (neurofibrillary tangles) clusters degenerating endings (neuritic plaques) cerebral cortex. This condition then be disease cause presenile (AD). For many decades an entity clearly delineated from more common senile dementia, although similar microscopical occurred two categories. In early I960’s Kidd (1963) Terry et al. (1964) demonstrated identical ultrastructural brains since also has been included (AD/SDAT).