作者: David A Grimes
DOI: 10.1016/S0140-6736(00)05299-5
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摘要: Investigators in Oxford have made many contributions to the understanding for potential relations between contraception genital-tract infections and infertility. A cohort study comparing return fertility among nulliparas after discontinuation of become pregnant is an example. In this long-term IUD use by was associated with a delay childbirth compared time those stopping oral contraceptives barrier methods. The investigators recommended that IUDs should be used sparingly nulliparous women years avoided. addition they speculated pelvic inflammatory disease might been culprit although their could not explore biological mechanisms. However reported strong associations upper genital tract found unreliable due selection bias confounding because there broader definition outcome than etiological hypothesis study. review evidence conducted WHO concludes benefits outweigh theoretical or proven risks. Nevertheless are still warned against view inconsistent relations.