作者: John R Rohde , Robert Bastidas , Rekha Puria , Maria E Cardenas
DOI: 10.1016/J.MIB.2008.02.013
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摘要: The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate undergoing morphogenic transitions ensure survival. Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel kinase substrates established the protein trafficking membranous network nucleus as platforms for signaling. These recent findings delineate distinct branches emanating from membrane-associated complexes control