Psychological morbidity associated with ovarian cancer screening: results from more than 23,000 women in the randomised trial of ovarian cancer screening (UKCTOCS).

摘要: Objective To examine the psychological sequelae associated with abnormal screening in United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Design Prospective, longitudinal randomised control trial. Setting Sixteen UKCTOCS centres. Sample Women aged 50–70 years to annual multimodal screening, ultrasound or groups. Methods Two groups were followed for 7 years: (1) a random sample (n = 1339), taken from all three study groups; and (2) an events (n = 22 035) women screens resulting need repeat testing either low higher level intensity. Main outcome measures Patient-reported measures anxiety (scores ranging 20 80) morbidity. Results In mean difference between scores after those following was 0.4 (95% CI −0.46, 1.27), it 0.37 0.23, 0.51). The risk morbidity only increased event requiring (OR 1.28; 95% CI 1.18, 1.39). ovarian cancer at both 6 weeks (OR 16.2; 9.19, 28.54) 6 months (OR 3.32; 1.91, 5.77) surgery. Conclusions Screening does not appear raise but is elevated by more intense screens, surgical treatment cancer.