Complications after Extended (D2) and Superextended (D3) Lymphadenectomy for Gastric Cancer: Analysis of Potential Risk Factors

作者: Daniele Marrelli , Corrado Pedrazzani , Alessandro Neri , Giovanni Corso , Alfonso De Stefano

DOI: 10.1245/S10434-006-9063-3

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摘要: Very few studies from Western centers have compared D2 and D3 dissection in the surgical treatment of gastric cancer. The aim prospective observational study reported here was to analyze postoperative outcome potential risk factors for complications following lymphadenectomy. A total 330 consecutive patients, which 251 submitted lymphadenectomy 79 were treated by lymphadenectomy, enrolled study. Twenty morbidity mortality studied means univariate multivariate analysis. Overall rates 34% (111 patients) 4% (14 patients), respectively. Abdominal abscess, anastomotic leakage, pleuropulmonary diseases pancreatitis most commonly observed complications. No differences morbidity, mean hospital stay between found. Multivariate analysis revealed that American Society Anesthesiologists’ (ASA) class II/III versus I, perioperative blood transfusions, low albumin serum levels independent predictors Age, radicality (R1/R2 vs. R0) independently predicted mortality. Mortality rate .5% 203 patients aged 75 years or younger who underwent curative surgery. Most deaths older than with non-curative represents a feasible procedure associated acceptable rates. In specialized centers, may be performed without increasing carefully selected patients. These techniques should avoided subgroups high

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