Correlation of Microsatellite Instability at Multiple Loci With Long-term Survival in Advanced Gastric Carcinoma
作者： Giovanni Corso
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摘要: Hypothesis Microsatellite instability (MSI) correlates with clinicopathologic characteristics and long-term prognosis in patients having gastric carcinoma. Design Analysis of prospectively collected data biologic material. Setting Tertiary University Hospital, Policlinico “Le Scotte,” Siena, Italy. Patients Two hundred fifty Main Outcome Measures Five mononucleotide repeats (BAT-26, BAT-25, NR-24, NR-21, NR-27) were analyzed these patients. Results An MSI phenotype was identified 63 (25.2%) correlated specific characteristics. Favorable confirmed for an univariate (P Conclusions Compared stable tumors, tumors have distinct features are associated a better prognosis. the MSI/5 very good
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