Association Between Atopic Disease and Anemia in US Children

摘要: Importance Atopic disease is associated with chronic inflammation, food allergen avoidance, and use of systemic immunosuppressant medications. All these factors have been shown to be anemia. Objective To investigate whether atopic increased risk childhood Design, Setting, Participants A cross-sectional survey laboratory assessment were conducted using data from the 1997-2013 US National Health Interview Survey (NHIS) that included 207 007 children adolescents 1999-2012 Nutrition Examination (NHANES) 30 673 adolescents. Analysis was between August 1, 2014, 28, 2015. Exposures Caregiver-reported history eczema, asthma, hay fever, and/or allergy. Main Outcomes Measures Anemia defined by caregiver report in NHIS hemoglobin levels for age sex NHANES. Results Data collected on NHIS, representing all pediatric age, sex, racial/ethnic, household educational level, income groups. The prevalence 9.5% (95% CI, 9.4%-9.7%) years health care–diagnosed 12.8% 12.6%-13.0%) 17.1% 16.9%-17.3%) 4.2% 4.1%-4.3%) allergy, 1.1% 1.1%-1.2%) In multivariable logistic regression models controlling race/ethnicity, annual income, highest level family, insurance coverage, number persons household, birthplace United States, anemia eczema 14 17 studies, asthma 11, fever 12, allergy 12. analysis across (with results reported as adjusted odds ratios [95% CIs]), any (1.83; 1.58-2.13), (1.31; 1.14-1.51), (1.57; 1.36-1.81), (2.08; 1.71-2.52) had higher ( P  = .02) (1.93; 1.04-3.59;  = .04) anemia, particularly microcytic (asthma: 1.61; 1.09-2.38;  = .02; eczema: 2.03; 1.20-3.46;  = .009) while not (0.85; 0.62-1.17;  = .33). Conclusions Relevance association reproducible multiple cohorts. Future studies are needed identify determinants