Natural antibodies to human retrovirus HTLV in a cluster of Japanese patients with adult T cell leukemia.

作者: M Robert-Guroff , Y Nakao , K Notake , Y Ito , A Sliski

DOI: 10.1126/SCIENCE.6760397

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摘要: Human T cell lymphoma leukemia virus (HTLV) is a human retrovirus (RNA tumor virus) that was originally isolated from few patients with leukemias or lymphomas involving mature lymphocytes. Here we report the serum of Japanese adult leukemia, but not tested normal donors, contains high titers antibodies to HTLV. These observations, together data Japan showing endemic in southwest Japan, suggest HTLV involved subtype malignancy, including leukemia.

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