The effect of EDTA instillations on the rate of development of encrustation and biofilms in Foley catheters.

摘要: The aim of this research was to examine whether a daily instillation tetra sodium ethylenediaminetetraacetic acid (EDTA) solution could reduce the rate at which encrustation by crystalline Proteus mirabilis biofilms blocks urinary catheters. Sets three bladder models were fitted with size 14 all-silicone Tetra EDTA instilled into catheter following biofilm development. Catheters examined digital photography and scanning electron microscopy for evidence encrustation. results showed that mean time blockage control catheters 45 h saline, 57 water 67 those exposed instillations solution. Statistical analysis confirmed on EDTA-treated significantly lower than control-treated devices (P = 0.047). This in vitro study indicates may have beneficial effects reducing complication biofilms.