Serial Pattern Learning in Senescent Rats: A Comparison of Acquisition Performance with Young and Hippocampal-Lesioned Rats

摘要: Abstract The acquisition of a serial pattern was assessed in young (3-month), senescent (24-month), and hippocampal-lesioned rats. All animals were trained for 25 days on four-element, nonmonotonic consisting 14, 0, 3, 7 food pellets, respectively. Young rats capable distinguishing among the elements series, with exception 3- 7-pellet elements, as indexed by running times. Conversely, largely incapable patterned responding, tracking performance intermediate between those old Results are discussed terms possible changes that accompany aging rodents, including age-related hippocampal system.