Radiochemistry and biostability of autologous leucocytes labelled with 99mTc-stannous colloid in whole blood

作者: Ross Hanna , Terry Braun , Alex Levendel , Fred Lomas

DOI: 10.1007/BF00448542

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摘要: Autologous leucocytes were labelled in whole blood by phagocytic uptake of 99mTc-stannous colloid. This colloid has a mean particle size 1.5 μm and labels with 81% efficiency. Individual cell uptakes were: granulocytes 42%, monocytes 39%. Isotonic sodium citrate added after the labelling procedure did solubilise excess but was not necessary for adequate removal Labelled shown vitro to be viable maintain normal bactericidal chemotactic capacity. Biodistribution, clearance rates dosimetry are presented. These results indicate that autologous can efficiently good residual function.

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