Neutrophil labeling with [99mTc]-technetium stannous colloid is complement receptor 3-mediated and increases the neutrophil priming response to lipopolysaccharide
作者： Hayley Gallagher , Stuart C. Ramsay , Jodie Barnes , Jacqueline Maggs , Nathan Cassidy
DOI: 10.1016/J.NUCMEDBIO.2005.12.014
关键词:
摘要: 99mTc]-technetium stannous colloid (TcSnC)-labeled white cells are used to image inflammation. Neutrophil labeling with TcSnC is probably phagocytic, but the phagocytic receptor involved not known. We hypothesised that complement 3 (CR3) plays a key role. Phagocytic could theoretically result in neutrophil activation or priming, affecting behaviour of labeled cells. Fluorescence-activated cell sorter (FACS) analysis side scatter measurements can assess and priming.
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