Does pregnancy immunize against breast cancer

作者: Reddish Ma , Krantz Mj , Agrawal B , Longenecker Bm

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摘要: Abstract Multiparity has been linked with protection against breast cancer. T cells from biparous women, but not nulliparous women or men, specifically proliferated in response to core peptide sequences of a human cancer-associated mucin (MUC-1). Two the were retested during first trimester their pregnancy, and MUC-1 mucin. These observations support hypothesis that there is natural immunization epitopes pregnancy which provides some development data also suggest certain synthetic peptides might be effective components “vaccines” for therapy prevention

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