The Science of Neoplasia and Its Relationship to Aging
作者： Robert E. Martell , Harvey Jay Cohen
关键词:
摘要: The biologic basis for cancer is clearly multidimensional and complex. This chapter systematically discusses the key elements of development, progression, treatment with a specific focus on role aging in these processes. Unfortunately, there no unifying explanation that describes essence cancer. There are, however, many epidemiologic links to aging. Biologic changes occur during probably increase likelihood developing Age-associated also impact significantly therapeutics. All areas need more research, but understanding them can help clinician at forefront prevention, diagnosis, an population.
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Douglas R Green, Apoptotic pathways: paper wraps stone blunts scissors. Cell. ,vol. 102, pp. 1- 4 ,(2000) , 10.1016/S0092-8674(00)00003-9
Ronit Pinkas-Kramarski, Iris Alroy, Yosef Yarden, ErbB receptors and EGF-like ligands: cell lineage determination and oncogenesis through combinatorial signaling. Journal of Mammary Gland Biology and Neoplasia. ,vol. 2, pp. 97- 107 ,(1997) , 10.1023/A:1026343528967
Woodring E. Wright, Jerry W. Shay, Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology. Nature Medicine. ,vol. 6, pp. 849- 851 ,(2000) , 10.1038/78592
Kari Alitalo, Manfred Schwab, Oncogene Amplification in Tumor Cells Advances in Cancer Research. ,vol. 47, pp. 235- 281 ,(1986) , 10.1016/S0065-230X(08)60201-8
Timothy S. Lewis, Paul S. Shapiro, Natalie G. Ahn, Signal Transduction through MAP Kinase Cascades Advances in Cancer Research. ,vol. 74, pp. 49- 139 ,(1998) , 10.1016/S0065-230X(08)60765-4
Carina J. Vessey, Christopher J. Norbury, Ian D. Hickson, Genetic disorders associated with cancer predisposition and genomic instability. Progress in Nucleic Acid Research and Molecular Biology. ,vol. 63, pp. 189- 221 ,(1999) , 10.1016/S0079-6603(08)60723-0
Bruce A. Chabner, Dan L. Longo, Cancer Chemotherapy and Biotherapy: Principles and Practice ,(1996)
Stuart H. Yuspa, The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture. Cancer Research. ,vol. 54, pp. 1178- 1189 ,(1994)
Edward B. Leof, Harold L. Moses, Gary D. Shipley, Anton Scott Goustin, Growth Factors and Cancer Cancer Research. ,vol. 46, pp. 1015- 1029 ,(1986)
M D Sklar, E Thompson, M J Welsh, M Liebert, J Harney, H B Grossman, M Smith, E V Prochownik, Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells. Molecular and Cellular Biology. ,vol. 11, pp. 3699- 3710 ,(1991) , 10.1128/MCB.11.7.3699