Oncogene Amplification in Tumor Cells

作者: Kari Alitalo , Manfred Schwab

DOI: 10.1016/S0065-230X(08)60201-8

关键词: Cancer cellDouble minuteGene duplicationNeuroblastomaCytotoxic T cellOncogeneCancer researchGeneSomatic cellBiologyMolecular biology

摘要: Publisher Summary This chapter summarizes the third mechanism of oncogene activation—oncogene amplification. It illustrates the various ways by which the oncogenic potential of …

参考文章(221)
T. W. Baba, E. H. Humphries, Formation of a transformed follicle is necessary but not sufficient for development of an avian leukosis virus-induced lymphoma. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 82, pp. 213- 216 ,(1985) , 10.1073/PNAS.82.1.213
Jim Battey, Christopher Moulding, Rebecca Taub, William Murphy, Timothy Stewart, Huntington Potter, Gilbert Lenoir, Philip Leder, The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma Cell. ,vol. 34, pp. 779- 787 ,(1983) , 10.1016/0092-8674(83)90534-2
Holly D. Abrams, Larry R. Rohrschneider, Robert N. Eisenman, Nuclear location of the putative transforming protein of avian myelocytomatosis virus Cell. ,vol. 29, pp. 427- 439 ,(1982) , 10.1016/0092-8674(82)90159-3
Alan Hall, Christopher J. Marshall, Nigel K. Spurr, Robin A. Weiss, Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1 Nature. ,vol. 303, pp. 396- 400 ,(1983) , 10.1038/303396A0
E. Gebhart, S. Bruderlein, A. H. Tulusan, K. V. Maillot, J. Birkmann, Incidence of double minutes, cytogenetic equivalents of gene amplification, in human carcinoma cells International Journal of Cancer. ,vol. 34, pp. 369- 373 ,(1984) , 10.1002/IJC.2910340313
Kari Alitalo, Gary Ramsay, J. Michael Bishop, Susan Ohlsson Pfeifer, Wendy W. Colby, Arthur D. Levinson, Identification of nuclear proteins encoded by viral and cellular myc oncogenes. Nature. ,vol. 306, pp. 274- 277 ,(1983) , 10.1038/306274A0