Use of antiretrovirals during pregnancy and breastfeeding in low-income and middle-income countries.

摘要: PURPOSE OF REVIEW: The purpose of the study was to review recent evidence on use antiretrovirals during pregnancy and breastfeeding in low-income middle-income settings. RECENT FINDINGS: Access antiretroviral prophylaxis strategies for HIV-infected pregnant women has increased globally but two-thirds need still do not receive even simplest regimen prevention mother-to-child transmission HIV most treatment it. combination low-resource settings is safe effective increasing supports starting ongoing at a CD4 cell count below 350/microl women. appropriate short-course prophylactic regimens with higher counts. New data prevent through demonstrate that both maternal extended infant are effective. SUMMARY: Antiretroviral can benefit mothers reduce risk transmission. Emerging effectiveness preventing encouraging likely influence practice future.