Optimal time on HAART for prevention of mother-to-child transmission of HIV.
作者： Carla J Chibwesha , Mark J Giganti , Nande Putta , Namwinga Chintu , Jessica Mulindwa
DOI: 10.1097/QAI.0B013E318229147E
关键词:
摘要: OBJECTIVES: To determine the impact of time between initiating highly active antiretroviral therapy (HAART) and delivery-duration antenatal HAART-on perinatal HIV infection. DESIGN: We conducted a retrospective cohort analysis pregnant HIV-infected women in Lusaka Zambia. Women our were receiving HAART had an infant polymerase chain reaction test 3 12 weeks life. METHODS: examined factors associated with infection performed locally weighted regression to examine effect duration on RESULTS: : From January 2007 March 2010 1813 met inclusion criteria. Mean gestational age at first visit was 21 (SD +/- 6) median CD4+ cell count 231 cells per microliter (interquartile range: 164-329) 13 range 8-19). Fifty-nine (3.3%) infants infected. Duration most important predictor transmission. Compared least before delivery for
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