Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells.
作者： Philippe Taupin
DOI: 10.7150/IJMS.5.127
关键词:
摘要: The pathogenesis of neurological diseases and disorders remains mostly unknown. Neuroinflammation has been proposed as a causative factor for diseases. confirmation that neurogenesis occurs in the adult brain neural stem cells (NSCs) reside central nervous system (CNS) mammals tremendous implications our understanding physio- pathology system. generation newborn neuronal is modulated during inflammation. This suggests involved disorders, particularly neuroinflammation. In this manuscript, we will review modulation We discuss role contribution neuroinflammation to therapeutic potential NSCs.
core.ac.uk 
sci-hub.se 参考文章(75)
Roopa S. Ghirnikar, Yuen Ling Lee, Lawrence F. Eng, Inflammation in traumatic brain injury: role of cytokines and chemokines Neurochemical Research. ,vol. 23, pp. 329- 340 ,(1998) , 10.1023/A:1022453332560
Stoll Guido, Jander Sebastian, Michael Schroeter, Detrimental and Beneficial Effects of Injury-Induced Inflammation and Cytokine Expression in the Nervous System Advances in Experimental Medicine and Biology. ,vol. 513, pp. 87- 113 ,(2003) , 10.1007/978-1-4615-0123-7_3
Charles G. Gross, Neurogenesis in the adult brain: death of a dogma Nature Reviews Neuroscience. ,vol. 1, pp. 67- 73 ,(2000) , 10.1038/35036235
P S Whitton, Inflammation as a causative factor in the aetiology of Parkinson's disease. British Journal of Pharmacology. ,vol. 150, pp. 963- 976 ,(2007) , 10.1038/SJ.BJP.0707167
Norman Latov, Gajanan Nilaver, Earl A. Zimmerman, William G. Johnson, Ann-Judith Silverman, Richard Defendini, Lucien Cote, Fibrillary astrocytes proliferate in response to brain injury: A study combining immunoperoxidase technique for glial fibrillary acidic protein and radioautography of tritiated thymidine Developmental Biology. ,vol. 72, pp. 381- 384 ,(1979) , 10.1016/0012-1606(79)90127-1
Philippe Taupin, Adult neurogenesis and neuroplasticity. Restorative Neurology and Neuroscience. ,vol. 24, pp. 9- 15 ,(2006)
F. -J. Mueller, S. R. McKercher, J. Imitola, J. F. Loring, S. Yip, S. J. Khoury, E. Y. Snyder, At the Interface of the Immune System and the Nervous System: How Neuroinflammation Modulates the Fate of Neural Progenitors In Vivo Opportunities and Challenges of the Therapies Targeting CNS Regeneration. pp. 83- 114 ,(2005) , 10.1007/3-540-27626-2_6
Eiji Tada, John R. Fike, Daniel H. Lowenstein, Jack M. Parent, Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat The Journal of Neuroscience. ,vol. 19, pp. 4508- 4519 ,(1999) , 10.1523/JNEUROSCI.19-11-04508.1999
Philippe Taupin, Adult neurogenesis in the mammalian central nervous system: functionality andpotential clinical interest. Medical Science Monitor. ,vol. 11, ,(2005)
Yan Yang, David S. Geldmacher, Karl Herrup, DNA Replication Precedes Neuronal Cell Death in Alzheimer's Disease The Journal of Neuroscience. ,vol. 21, pp. 2661- 2668 ,(2001) , 10.1523/JNEUROSCI.21-08-02661.2001