Infectious Microecology and Immunology

作者: Hongyan Diao , Guangying Cui , Jianing Chen , Yingfeng Wei

DOI: 10.1007/978-3-662-43883-1_3

关键词:

摘要: Infectious microecology is a branch of that uses microecological theory and methods to investigate the appearance, development outcome infection. The main purpose this chapter pathogenesis infection its clinical manifestations, preventions therapies. Under normal conditions, gut microflora exists in state equilibrium with host has been described as separate “organ” adapted human physiology. From moment birth, neonatal intestine confronted potent immunostimulatory substances while body surfaces are protected from environmental microbial exposure during fetal life [1]. Microbial antigenic challenge required for maturation several physiological anatomical functions intestinal epithelial barrier (IEB) [2]. Commensal bacteria regulate innate adaptive immunity provide stimuli ongoing repair restitution IEB [3]. Colonization by pathogenic (or) dysmature response antigen may result flagrant inflammatory [4].

参考文章(139)
David A. Hill, David Artis, Intestinal Bacteria and the Regulation of Immune Cell Homeostasis Annual Review of Immunology. ,vol. 28, pp. 623- 667 ,(2010) , 10.1146/ANNUREV-IMMUNOL-030409-101330
Inna Sekirov, Shannon L. Russell, L. Caetano M. Antunes, B. Brett Finlay, Gut Microbiota in Health and Disease Physiological Reviews. ,vol. 90, pp. 859- 904 ,(2010) , 10.1152/PHYSREV.00045.2009
Xiaomin Wu, Xiaoxuan Lin, Jinyu Tan, Zishan Liu, Jinshen He, Fan Hu, Yu Wang, Minhu Chen, Fen Liu, Ren Mao, Cellular and molecular mechanisms of intestinal fibrosis World Journal of Gastroenterology. ,vol. 18, pp. 3635- 3661 ,(2012) , 10.3748/WJG.V18.I28.3635
James A. Deane, Michael J. Hickey, Molecular mechanisms of leukocyte trafficking in T-cell-mediated skin inflammation: insights from intravital imaging. Expert Reviews in Molecular Medicine. ,vol. 11, pp. 1- 21 ,(2009) , 10.1017/S146239940900115X
Minoru Takahashi, Yumi Ishida, Daisuke Iwaki, Kazuko Kanno, Toshiyuki Suzuki, Yuichi Endo, Yoshimi Homma, Teizo Fujita, Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D Journal of Experimental Medicine. ,vol. 207, pp. 29- 37 ,(2010) , 10.1084/JEM.20090633
Megan K. Levings, Romina Sangregorio, Claudia Sartirana, Anna Lisa Moschin, Manuela Battaglia, Paul C. Orban, Maria-Grazia Roncarolo, Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells Journal of Experimental Medicine. ,vol. 196, pp. 1335- 1346 ,(2002) , 10.1084/JEM.20021139
Gretta L. Stritesky, Stephen C. Jameson, Kristin A. Hogquist, Selection of Self-Reactive T Cells in the Thymus Annual Review of Immunology. ,vol. 30, pp. 95- 114 ,(2012) , 10.1146/ANNUREV-IMMUNOL-020711-075035
Roberto J Cieza, Anthony T Cao, Yingzi Cong, Alfredo G Torres, Immunomodulation for gastrointestinal infections Expert Review of Anti-infective Therapy. ,vol. 10, pp. 391- 400 ,(2012) , 10.1586/ERI.11.176
Ciarán P. Kelly, Lorraine Kyne, The host immune response to Clostridium difficile. Journal of Medical Microbiology. ,vol. 60, pp. 1070- 1079 ,(2011) , 10.1099/JMM.0.030015-0