Kinetics of diarrhetic shellfish poisoning toxins, okadaic acid, dinophysistoxin-1, pectenotoxin-6 and yessotoxin in scallops Patinopecten yessoensis
作者： Toshiyuki SUZUKI , Tomoji IGARASHI , Kazuhiko ICHIMI , Masatoshi WATAI , Megumi SUZUKI
DOI: 10.1111/J.1444-2906.2005.01049.X
关键词:
摘要: Four toxins, okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-6 (PTX6), and yessotoxin (YTX), all associated with diarrhetic shellfish poisoning (DSP), were administered via syringe to Scallops Patinopecten yessoensis their distribution in the hepatopancreas, adductor muscle, combined other tissues (mantle, gill, gonad) was analyzed by liquid chromatography-mass spectrometry. Toxins exclusively remained hepatopancreas irrespective of injection site, muscle or hepatopancreas. When injected into OA, DTX1, YTX metabolized 7-O-palmitoylOA, 7-O-palmitoylDTX1 45-hydroxyyessotoxin (45OH-YTX), respectively. Such metabolic changes insignificant when toxins muscle. The residual ratio for each toxin less than 20%. Mortalities scallops treated PTX6 lower those toxins.
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