15-Year Experience of 18F-FDG PET Imaging in Response Assessment and Restaging After Definitive Treatment of Merkel Cell Carcinoma

摘要: The objective of this study was to evaluate the utility 18F-FDG PET in restaging and response assessment patients who underwent definitive treatment for Merkel cell carcinoma (MCC). Methods: A retrospective review undergoing imaging MCC between January 1997 October 2010 at Peter MacCallum Cancer Centre with follow-up until February 2015 performed. Data analysis performed on were treated definitively post-treatment either as a scan ongoing monitoring, suspicion recurrence, or suitability salvage within 1–6 mo treatment. Management plans recorded prospectively before compared post-imaging management assess impact per our previously defined categories: high if primary modality intent changed medium radiotherapy technique dose altered. In total, 62 included analysis. Thirty-six 53 scans, 37 response-assessment scan. median group 5.3 y (95% confidence interval [CI], 4.6–9.4), it 5.7 CI, 4.3–10.8) group. Results: Restaging scans had 24 cases (45%) 6 (11%). group, complete metabolic (CMR). Patients without CMR 15% 1-y overall survival 0.04–0.55). Those an 88% 2-y 0.75–1.00) 68% 5-y 0.49–0.95). presence (P