Identification of ankylosing spondylitis-associated genes by expression profiling

作者: HUI MA , DABO XU , QIANG FU

DOI: 10.3892/IJMM.2012.1047

关键词:

摘要: Ankylosing spondylitis (AS) is a chronic inflammation attacking the sacroiliac joints and spine. Certain genes have been associated with occurrence of AS. Gene chip data were utilized to recognize AS for association clinical diagnosis biomedical study. Microarray expression acquired from public microarray database GEO (gene omnibus), AS-related obtained by differential gene profiling. The transcriptional translational levels these further examined. three shown be upregulated in mouse model real-time PCR Elisa assay, respectively. Differential was identified analysis data, contributing advancement understanding pathogenesis

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