CD11b regulates antibody class switching via induction of AID.

作者: Seohyun Park , Hyunsub Sim , Hye-In Kim , Daecheol Jeong , Guang Wu

DOI: 10.1016/J.MOLIMM.2017.04.005

关键词:

摘要: … Here, we report the induction of CD11b in activated B2 B cells and define its unexpected role in immunoglobulin heavy chain class switch recombination (CSR). LPS-activated B cells …

参考文章(41)
Laurence Arbibe, Jean-Paul Mira, Nicole Teusch, Lois Kline, Mausumee Guha, Nigel Mackman, Paul J. Godowski, Richard J. Ulevitch, Ulla G. Knaus, Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway. Nature Immunology. ,vol. 1, pp. 533- 540 ,(2000) , 10.1038/82797
Robert L. Coffman, Deborah A. Lebman, Paul Rothman, Mechanism and Regulation of Immunoglobulin Isotype Switching Advances in Immunology. ,vol. 54, pp. 229- 270 ,(1993) , 10.1016/S0065-2776(08)60536-2
T M McIntyre, A D Steinberg, K L Holmes, D L Kastner, CD5+ peritoneal B cells express high levels of membrane, but not secretory, C mu mRNA. Journal of Immunology. ,vol. 146, pp. 3639- 3645 ,(1991)
Z. Chen, A. Getahun, X. Chen, Y. Dollin, J. C. Cambier, J. H. Wang, Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. Journal of Immunology. ,vol. 195, pp. 5461- 5471 ,(2015) , 10.4049/JIMMUNOL.1501375
Hongsheng Wang, Jian-xin Lin, Peng Li, Jeff Skinner, Warren J. Leonard, Herbert C. Morse, New insights into heterogeneity of peritoneal B-1a cells. Annals of the New York Academy of Sciences. ,vol. 1362, pp. 68- 76 ,(2015) , 10.1111/NYAS.12791
Tatsuo Kinashi, Intracellular signalling controlling integrin activation in lymphocytes Nature Reviews Immunology. ,vol. 5, pp. 546- 559 ,(2005) , 10.1038/NRI1646
Yoshiteru Sasaki, Emmanuel Derudder, Elias Hobeika, Roberta Pelanda, Michael Reth, Klaus Rajewsky, Marc Schmidt-Supprian, Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation Immunity. ,vol. 24, pp. 729- 739 ,(2006) , 10.1016/J.IMMUNI.2006.04.005
Hyokjoon Kwon, Danielle Thierry-Mieg, Jean Thierry-Mieg, Hyoung-Pyo Kim, Jangsuk Oh, Chainarong Tunyaplin, Sebastian Carotta, Colleen E. Donovan, Matthew L. Goldman, Prafullakumar Tailor, Keiko Ozato, David E. Levy, Stephen L. Nutt, Kathryn Calame, Warren J. Leonard, Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors Immunity. ,vol. 31, pp. 941- 952 ,(2009) , 10.1016/J.IMMUNI.2009.10.008
Jun Kunisawa, Masashi Gohda, Eri Hashimoto, Izumi Ishikawa, Morio Higuchi, Yuji Suzuki, Yoshiyuki Goto, Casandra Panea, Ivaylo I. Ivanov, Risa Sumiya, Lamichhane Aayam, Taichi Wake, So Tajiri, Yosuke Kurashima, Shiori Shikata, Shizuo Akira, Kiyoshi Takeda, Hiroshi Kiyono, Microbe-dependent CD11b + IgA + plasma cells mediate robust early-phase intestinal IgA responses in mice Nature Communications. ,vol. 4, pp. 1772- 1772 ,(2013) , 10.1038/NCOMMS2718
Keunwook Lee, Prathyusha Gudapati, Srdjan Dragovic, Charles Spencer, Sebastian Joyce, Nigel Killeen, Mark A. Magnuson, Mark Boothby, Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways Immunity. ,vol. 32, pp. 743- 753 ,(2010) , 10.1016/J.IMMUNI.2010.06.002