Sudden death in young competitive athletes: clinicopathologic correlations in 22 cases

作者: Domenico Corrado , Gaetano Thiene , Andrea Nava , Lino Rossi , Natale Pennelli

DOI: 10.1016/0002-9343(90)90176-E

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摘要: Abstract purpose: To investigate the pathologic substrates of sudden death in young competitive athletes. patients and methods: Twenty-two cases athletes occurring Veneto region (northern Italy) period January 1979 to December 1989 were studied by postmortem examination. The included 19 males three females, ranging age from 11 35 years (mean, 23 years). results: In 18 cases, occurred during (16 cases) or immediately after (two a sport activity. 10 subjects, was apparently first sign disease. Postmortem examination disclosed that this fatality due arrhythmic cardiac arrest 17 cases; among these, right ventricular cardiomyopathy, also known as "right dysplasia," most frequently encountered cardiovascular disease (six cases), followed atherosclerotic coronary artery (four conduction system pathology (three anomalous origin wrong aortic sinus mitral valve prolapse cases). two athletes, abrupt lethal complication "mechanical" consisted pulmonary embolism rupture aorta; cerebral cause. All with cardiomyopathy died effort, had history palpitations and/or syncope. Whenever available, electrocardiographic (ECG) tracings showed inverted T waves precordial leads left bundle branch block arrhythmias. conclusions: Clinicopathologic correlations indicate Italy, is not so rare diseases associated risk arrest, seems account for majority athletes; disorder can be suspected life on basis prodromal symptoms ECG signs.

参考文章(31)
FONTAINE G, FRANK R, TNET L, GUIRAUDON G, CABROL C, CHOMETTE G, GROSGOGEAT Y, Arrhythmogenic right ventricular dysplasia: a clinical model for the study of chronic ventricular tachycardia. Japanese Circulation Journal-english Edition. ,vol. 48, pp. 515- 538 ,(1984) , 10.1253/JCJ.48.515
Andrea Nava, Bruno Canciani, Gianfranco Buja, Bortolo Martini, Luciano Daliento, Roldano Scognamiglio, Gaetano Thiene, Electrovectorcardiographic study of negative T waves on precordial leads in arrhythmogenic right ventricular dysplasia: Relationship with right ventricular volumes Journal of Electrocardiology. ,vol. 21, pp. 239- 245 ,(1988) , 10.1016/0022-0736(88)90098-2
Saroja Bharati, Arthur S. Granston, Philip R. Liebson, Henry S. Loeb, Kenneth M. Rosen, Maurice Lev, The conduction system in mitral valve prolapse syndrome with sudden death American Heart Journal. ,vol. 101, pp. 667- 670 ,(1981) , 10.1016/0002-8703(81)90235-0
On Topaz, Jesse E. Edwards, Pathologic Features of Sudden Death in Children, Adolescents, and Young Adults Chest. ,vol. 87, pp. 476- 482 ,(1985) , 10.1378/CHEST.87.4.476
Barry J. Maron, Structural features of the athlete heart as defined by echocardiography Journal of the American College of Cardiology. ,vol. 7, pp. 190- 203 ,(1986) , 10.1016/S0735-1097(86)80282-0
C Blomstrom-Lundqvist, K Selin, R Jonsson, S R Johansson, D Schlossman, S B Olsson, Cardioangiographic findings in patients with arrhythmogenic right ventricular dysplasia. Heart. ,vol. 59, pp. 556- 563 ,(1988) , 10.1136/HRT.59.5.556
Andrea Nava, Gaetano Thiene, Bruno Canciani, Roldano Scognamiglio, Luciano Daliento, Gianfranco Buja, Bortolo Martini, Paolo Stritoni, Giuseppe Fasoli, Familial occurrence of right ventricular dysplasia: A study involving nine families Journal of the American College of Cardiology. ,vol. 12, pp. 1222- 1228 ,(1988) , 10.1016/0735-1097(88)92603-4
E Chesler, R A King, J E Edwards, The myxomatous mitral valve and sudden death. Circulation. ,vol. 67, pp. 632- 639 ,(1983) , 10.1161/01.CIR.67.3.632
Gaetano Thiene, Natale Pennelli, Lino Rossi, Cardiac conduction system abnormalities as a possible cause of sudden death in young athletes Human Pathology. ,vol. 14, pp. 704- 709 ,(1983) , 10.1016/S0046-8177(83)80143-9