Serologic response after vaccination against influenza (A/H1N1)pdm09 in children with renal disease receiving oral immunosuppressive drugs
作者： Seiji Tanaka , Tomoko Saikusa , Yuno Katafuchi , Kosuke Ushijima , Yasushi Ohtsu
DOI: 10.1016/J.VACCINE.2015.06.049
关键词:
摘要: A limited number of reports are available regarding the effect influenza vaccine in pediatric patients receiving steroid and immunosuppressant therapy. The A(H1N1)pdm09 was administered to 15 children with renal disease who were therapy (treatment group) 23 not these drugs (non-treatment group). Titer transition hemagglutination inhibition antibody compared between 2 groups immediately before vaccination 4 weeks 6 months after vaccination. Multivariate analysis showed a significant correlation geometric mean titer, SCR, SPR age, while no observed treatment efficacy. No serious adverse reactions occurred This strain is present existing vaccines, A(H1N1)pdm09HA alone 2009. this study had previously been exposed strain. Therefore, we evaluated without effects or past infection A(H3N2) previous year.
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