Neonatal Morbidities of Fetal Growth Restriction: Pathophysiology and Impact.

摘要: Being born small lays the foundation for short-term and long-term implications life. Intrauterine or fetal growth restriction describes pregnancy complication of pathological reduced growth, leading to significant perinatal mortality morbidity, subsequent deficits. Placental insufficiency is principal cause FGR, which in turn underlies a chronic undersupply oxygen nutrients fetus. The neonatal morbidities associated with FGR depend on timing onset placental dysfunction restriction, its severity, gestation at birth infant. In this review, we explore pathophysiological mechanisms involved development major their impact health Fetal cardiovascular adaptation altered organ during are contributors postnatal consequences FGR. Clinical presentation, diagnostic tools management strategies presented. We also present information current status targeted therapies. A better understanding will enable early detection, monitoring potential adverse outcomes newborn period beyond.