Multiple forms of plasminogen activator in human breast tumors.

摘要: Total plasminogen activator (PA) activity, tissue-type PA (t-PA) urokinase-like and immunoreactive t-PA were measured in benign breast tumors (fibroadenomas), primary carcinomas, axillary node metastases, chest wall recurrences. activity did not differ significantly the different types of tumors. However, contained predominantly activity. Urokinase-like was higher malignant compared with group. Both lower recurrences carcinomas. The ratio to urokinase decreased between stages 1 3 Also, levels 2 stage 1. No correlation found (either total or its forms) tumor grade, histological type, presence absence metastases.