摘要: Gastroesophageal reflux disease (GERD) may manifest typically with heartburn and regurgitation or atypically as laryngitis, asthma, cough, noncardiac chest pain. The diagnosis of these atypical manifestations be difficult for primary care physicians because most patients do not have regurgitation. Diagnostic tests low specificity it is to establish a cause-and-effect association between GERD symptoms. Response aggressive acid suppression often the commonly employed initial tool indicate etiology in patient