Aerosol synthesis of macroporous silica adsorbents with high performance in paclitaxel purification from plant cell cultures
作者： Hye Ran Jang , Jin-Hyun Kim , Kyeong Youl Jung
DOI: 10.1016/J.JIEC.2014.01.030
关键词:
摘要: Abstract Macroporous spherical silica particles having high performance for the purification of paclitaxel were synthesized by spray pyrolysis using polystyrene nanoparticles as a template. In terms increasing purity and yield paclitaxel, macroporous showed better than mesoporous surface area well commercial sylopute. The generation with sacrifice losing was proved to be helpful enhancing adsorbents purification. As result, (67.3%) (80.0%) achieved prepared pyrolysis.
elsevier.com
sci-hub.se 参考文章(24)
Hyeon-Jeong Oh, Hye Ran Jang, Kyeong Youl Jung, Jin-Hyun Kim, Evaluation of adsorbents for separation and purification of paclitaxel from plant cell cultures Process Biochemistry. ,vol. 47, pp. 331- 334 ,(2012) , 10.1016/J.PROCBIO.2011.11.004
Insoo Kang, Jin-Hyun Kim, Effect of Reactor Type on the Purification Efficiency of Paclitaxel in the Increased Surface Area Fractional Precipitation Process Separation and Purification Technology. ,vol. 99, pp. 14- 19 ,(2012) , 10.1016/J.SEPPUR.2012.08.025
Min-Gyeong Han, Keum-Young Jeon, Sungyong Mun, Jin-Hyun Kim, Development of a micelle-fractional precipitation hybrid process for the pre-purification of paclitaxel from plant cell cultures Process Biochemistry. ,vol. 45, pp. 1368- 1374 ,(2010) , 10.1016/J.PROCBIO.2010.05.010
Ji-Yeon Lee, Jin-Hyun Kim, Evaluation of the effect of crude extract purity and pure paclitaxel content on the increased surface area fractional precipitation process for the purification of paclitaxel Process Biochemistry. ,vol. 47, pp. 2388- 2397 ,(2012) , 10.1016/J.PROCBIO.2012.09.023
Sang-Hyun Pyo, Bong-Kyu Song, Chang-Hun Ju, Byung-Hee Han, Ho-Joon Choi, Effects of absorbent treatment on the purification of paclitaxel from cell cultures of Taxus chinensis and yew tree Process Biochemistry. ,vol. 40, pp. 1113- 1117 ,(2005) , 10.1016/J.PROCBIO.2004.03.004
Sungyong Mun, Nien-Hwa Linda Wang, Optimization of productivity in solvent gradient simulated moving bed for paclitaxel purification Process Biochemistry. ,vol. 43, pp. 1407- 1418 ,(2008) , 10.1016/J.PROCBIO.2008.08.011
J.H. Kim, I.S. Kang, H.K. Choi, S.S. Hong, H.S. Lee, A novel prepurification for paclitaxel from plant cell cultures Process Biochemistry. ,vol. 37, pp. 679- 682 ,(2002) , 10.1016/S0032-9592(01)00247-3
Li Yang, Tianwei Tan, Liqun Zhang, Process utilized oligo-β-cyclodextrin substituted agarose gel medium for efficient purification of paclitaxel from Taxus cuspidata Separation and Purification Technology. ,vol. 68, pp. 119- 124 ,(2009) , 10.1016/J.SEPPUR.2009.04.018
Hyeon-Jeong Oh, Hye Ran Jang, Kyeong Youl Jung, Jin-Hyun Kim, Evaluation of surface area of mesoporous silica adsorbents for separation and purification of paclitaxel Microporous and Mesoporous Materials. ,vol. 180, pp. 109- 113 ,(2013) , 10.1016/J.MICROMESO.2013.06.009
Jian-Jiang Zhong, Plant cell culture for production of paclitaxel and other taxanes Journal of Bioscience and Bioengineering. ,vol. 94, pp. 591- 599 ,(2002) , 10.1016/S1389-1723(02)80200-6